Therapeutics for Parkinson's disease
The subsequent introduction of levodopa and the demonstration that dopamine loss is the key pathological feature of Parkinson's disease (PD) have revolutionized the field of Parkinson’s disease therapeutics. Nearly 15 percent of people with Parkinson’s disease have motor symptoms that are not well-controlled with levodopa. Another potential therapy forParkinson’s disease is transplantation of dopaminergic tissue. A group of drugs that act directly on dopaminergic receptors called Dopamine agonists are used as adjuncts to levodopa in the treatment of Parkinson’s disease.